4-HNE ELISA Kits

4-HNE ELISA kits are designed for the specific detection of 4-hydroxynonenal in biological samples. 4-Hydroxynonenal is a compound that is metabolized in humans and can be detected in CSF, urine, fecal, and serum samples. It has the chemical formula C9H16O2. 4-Hydroxynonenal (HNE), a major product of lipid peroxidation, plays a role in signal transduction and can influence cell cycle events in a concentration-dependent manner. Cells with the capacity to exclude HNE from the intracellular environment at a faster rate are relatively more resistant to apoptosis caused by hydrogen peroxide, UVA, superoxide anion, and pro-oxidant xenobiotics as well as by HNE, suggesting that HNE may be a common denominator in mechanisms of apoptosis caused by oxidative stress.¹ Click on the ELISA products below and visit the supplier for more information, including assay sensitivity and target specificity.