XIAP ELISA kits are immunoassay tools for the measurement of the protein X-linked inhibitor of apoptosis, which is encoded by the XIAP gene in humans. Functionally, this protein is reported to be a multi-functional protein, which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. The canonical protein structure is reported to have an amino acid length of 497 residues, a mass of 56.7 kDa, and is a member of the IAP protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be expressed in colonic crypts. The protein has been noted to be post-translationally ubiquitinated. The XIAP gene has been associated with the disease, Lymphoproliferative syndrome. Other alias names for this target include BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3, and API3.
The detection range for different XIAP ELISA kits can vary, with some assays measuring target concentrations as low as 13.7 pg/mL and as high as 600 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.