PDK1 ELISA kits are immunoassay tools for the measurement of the protein pyruvate dehydrogenase kinase 1, which is encoded by the PDK1 gene in humans. Functionally, this protein is a reported kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. The canonical protein structure is reported to have an amino acid length of 436 residues, a mass of 49.2 kDa, and is a member of the PDK/BCKDK protein kinase protein family. It is known to be localized in the mitochondria and is reported to be highly expressed in the heart. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. Other alias names for this target include pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial, PDH kinase 1, mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1, and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial.
Some PDK1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.