PDGFRA ELISA kits are immunoassay tools for the measurement of the protein platelet derived growth factor receptor alpha, which is encoded by the PDGFRA gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. The canonical protein structure is reported to have an amino acid length of 1089 residues, a mass of 122.7 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the golgi and cell membrane and is notably expressed in platelets. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. The PDGFRA gene has been associated with the disease, Gastrointestinal stromal tumor. Other alias names for this target include PDGFR-2, PDGFR2, CD140 antigen-like family member A, CD140a antigen, PDGF-R-alpha, and CD140A.
There are PDGFRA ELISA kits that can detect a target at concentrations as low as 15.6 pg/mL and as high as 120 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.