PCNA ELISA kits are immunoassay tools for the measurement of the protein proliferating cell nuclear antigen, which is encoded by the PCNA gene in humans. Functionally, this protein is reported to be an auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. The canonical protein structure is reported to have an amino acid length of 261 residues, a mass of 28.8 kDa, and is a member of the PCNA protein family. It is known to be localized in the nucleus. The protein has been noted to be post-translationally methylated, ubiquitinated, sumoylated, acetylated and phosphorylated. The PCNA gene has been associated with the disease, Ataxia-telangiectasia-like disorder. Other alias names for this target include DNA polymerase delta auxiliary protein, cyclin, and ATLD2.
The detection range for different PCNA ELISA kits can vary, with some assays measuring target concentrations as low as 31.25 pg/mL and as high as 6000 µg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.