FLT3 ELISA kits are immunoassay tools for the measurement of the protein fms related receptor tyrosine kinase 3, which is encoded by the FLT3 gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. The canonical protein structure is reported to have an amino acid length of 993 residues, a mass of 112.9 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the ER and membrane and is notably expressed in bone marrow, in hematopoietic stem cells, in myeloid progenitor cells and in granulocyte/macrophage progenitor cells. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. The FLT3 gene has been associated with the disease, Leukemia. Other alias names for this target include FLK-2, FLK2, STK1, receptor-type tyrosine-protein kinase FLT3, CD135 antigen, and CD135.
Some FLT3 ELISA kits can detect targets at levels as low as 1.563 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.