DCX ELISA kits are immunoassay tools for the measurement of the protein doublecortin, which is encoded by the DCX gene in humans. Functionally, this protein is known to be a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. The canonical protein structure is reported to have an amino acid sequence of 365 residues and a mass of 40.6 kDa. It is known to be localized in the cytoplasm and is reported to be highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The DCX gene has been associated with the disease, Lissencephaly. Other alias names for this target include DC, LISX, SCLH, XLIS, neuronal migration protein doublecortin, doublecortex, doublin, and DBCN.
There are DCX ELISA kits that can detect a target at concentrations as low as 5 ng/L and as high as 400 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.