CTLA4 ELISA kits are immunoassay tools for the measurement of the protein cytotoxic T-lymphocyte associated protein 4, which is encoded by the CTLA4 gene in humans. Functionally, this protein is known to be involved in adaptive immune responses and DNA damage pathways. The canonical protein structure is reported to have an amino acid sequence of 223 residues and a mass of 24.7 kDa. It is known to be localized in the cell membrane and is reported to be widely expressed with highest levels in lymphoid tissues. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated and phosphorylated. The CTLA4 gene has been associated with the disease, Systemic lupus erythematosus. Other alias names for this target include CD, CD152, CELIAC3, GRD4, GSE, IDDM12, cytotoxic T-lymphocyte protein 4, and ALPS5.
The detection range for different CTLA4 ELISA kits can vary, with some assays measuring target concentrations as low as 0.78 pg/mL and as high as 640 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.