ATM ELISA kits are immunoassay tools for the measurement of the protein ATM serine/threonine kinase, which is encoded by the ATM gene in humans. Functionally, this protein is a serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. The canonical protein structure is reported to have an amino acid length of 3056 residues, a mass of 350.7 kDa, and is a member of the PI3/PI4-kinase protein family. It is known to be localized in the nucleus, cytoplasmic vesicles, and cytoplasm. The protein has been noted to be post-translationally acetylated and phosphorylated. The ATM gene has been associated with the disease, Ataxia telangiectasia. Other alias names for this target include ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1, and AT1.
The detection range for different ATM ELISA kits can vary, with some assays measuring target concentrations as low as 6.25 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.