The following OCRL inositol polyphosphate-5-phosphatase ELISA kits are useful research tools for the measurement of OCRL inositol polyphosphate-5-phosphatase in biological samples. In humans this protein is encoded by the OCRL gene. This protein is known to catalyze the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2. The canonical protein structure is reported to have an amino acid length of 901 residues, a mass of 104.2 kDa, and is a member of the Inositol 1,4,5-trisphosphate 5-phosphatase type II protein family. Its subcellular location is known to be in the cytoplasm. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Lowe oculocerebrorenal syndrome. This protein may also be known as Dent-2, INPP5F, LOCR, NPHL2, OCRL-1, OCRL1, inositol polyphosphate 5-phosphatase OCRL, and DENT2.
Some OCRL inositol polyphosphate-5-phosphatase ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.