The following NPHS1 adhesion molecule, nephrin ELISA kits are useful research tools for the measurement of NPHS1 adhesion molecule, nephrin in biological samples. In humans this protein is encoded by the NPHS1 gene. This protein is believed to play a role in the development or function of the kidney glomerular filtration barrier. The canonical protein structure is reported to have an amino acid length of 1241 residues, a mass of 134.7 kDa, and is a member of the Immunoglobulin protein superfamily. Its subcellular location is known to be in the cell membrane. In addition, it is notably expressed in podocytes of kidney glomeruli. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated and glycosylated. The gene encoding this protein has been associated with the disease, Nephrotic syndrome. This protein may also be known as NPHN, nephrin, NPHS1, nephrin, nephrosis 1, congenital, Finnish type (nephrin), renal glomerulus-specific cell adhesion receptor, and CNF.
The detection range for different NPHS1 adhesion molecule, nephrin ELISA kits can vary, with some assays measuring target concentrations as low as 7.81 pg/mL and as high as 100 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.