The following scribble planar cell polarity protein ELISA kits are useful research tools for the measurement of scribble planar cell polarity protein in biological samples. In humans this protein is encoded by the SCRIB gene. This protein is known to be a scaffold protein involved in different aspects of polarized cell differentiation regulating epithelial and neuronal morphogenesis and T-cell polarization. The canonical protein structure is reported to have an amino acid length of 1630 residues, a mass of 174.9 kDa, and is a member of the LAP (LRR and PDZ) protein family. Its subcellular location is known to be in the cell membrane and cytoplasm. In addition, it is reported to be expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and palmitoylated. The gene encoding this protein has been associated with the disease, Neural tube defects. This protein may also be known as SCRB1, SCRIB1, Vartul, oSCRIB, protein scribble homolog, and CRIB1.
The detection range for different scribble planar cell polarity protein ELISA kits can vary, with some assays measuring target concentrations as low as 78 pg/mL and as high as 5000 pg/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.