The following UPF3B regulator of nonsense mediated mRNA decay ELISA kits are useful research tools for the measurement of UPF3B regulator of nonsense mediated mRNA decay in biological samples. In humans this protein is encoded by the UPF3B gene. This protein is known to be a RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs. The canonical protein structure is reported to have an amino acid length of 483 residues, a mass of 57.8 kDa, and is a member of the DNA2/NAM7 helicase protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be expressed in testis, uterus, prostate, heart, muscle, brain, spinal cord and placenta.. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. The gene encoding this protein has been associated with the disease, Intellectual developmental disorder. This protein may also be known as UPF3 regulator of nonsense transcripts homolog B, UPF3B pseudogene 1, UPF3B pseudogene 2, UPF3B pseudogene 3, and regulator of nonsense transcripts 3B.
There are UPF3B regulator of nonsense mediated mRNA decay ELISA kits that can detect a target at concentrations as low as 0.313 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.