The following notch receptor 3 ELISA kits are useful research tools for the measurement of notch receptor 3 in biological samples. In humans this protein is encoded by the NOTCH3 gene. This protein is known to function as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. The canonical protein structure is reported to have an amino acid length of 2321 residues, a mass of 243.6 kDa, and is a member of the NOTCH protein family. Its subcellular location is known to be in the nucleus and cell membrane. In addition, it is widely expressed across many tissue types. In certain instances, it is also post-translationally glycosylated, cleaved and phosphorylated. The gene encoding this protein has been associated with the disease, Cerebral arteriopathy. This protein may also be known as CADASIL1, CASIL, IMF2, LMNS, neurogenic locus notch homolog protein 3, Notch homolog 3, and CADASIL.
The detection range for different notch receptor 3 ELISA kits can vary, with some assays measuring target concentrations as low as 70 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.