These PTEN Induced Putative Kinase 1 ELISA kits are immunodetection tools for measuring specific protein levels in biological samples. PTEN Induced Putative Kinase 1 is an alias of the human PINK1 gene, which encodes the protein, PTEN induced kinase 1. Notably, PTEN Induced Putative Kinase 1 is known to play a role in autophagy pathways and the cellular response to hypoxia, among other functions. The PINK1 protein is 581 amino acid residues in length and 62.8 kilodaltons in mass. However, as many as 2 protein isoforms have been identified. It is localized to the mitochondria and cytoplasm of the cell. In terms of tissue specificity, it is reported to be highly expressed in heart, skeletal muscle and testis, and at lower levels in the brain, placenta, liver, kidney, pancreas, prostate, ovary and small intestine. This protein is known to be cleaved and phosphorylated. Other names for this target antigen include serine/threonine-protein kinase PINK1, mitochondrial and PTEN induced putative kinase 1.
The detection range for different PTEN Induced Putative Kinase 1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.