SDHAF2 ELISA kits are immunoassay tools for the measurement of the protein succinate dehydrogenase complex assembly factor 2, which is encoded by the SDHAF2 gene in humans. Functionally, this protein is known to play an important role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. The canonical protein structure is reported to have an amino acid length of 166 residues, a mass of 19.6 kDa, and is a member of the SDHAF2 protein family. It is known to be localized in the mitochondria. The SDHAF2 gene has been associated with the disease, Paragangliomas. Other alias names for this target include PGL2, SDH5, hSDH5, succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, and C11orf79.
The detection range for different SDHAF2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.313 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.