The following Platelet Derived Growth Factor Receptor Beta ELISA kits are useful research tools for the measurement of platelet derived growth factor receptor beta in biological samples. In humans this protein is encoded by the PDGFRB gene. This protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. The canonical protein structure is reported to have an amino acid length of 1106 residues, a mass of 124 kDa, and is a member of the Tyr protein kinase protein family. Its subcellular location is known to be in the cytoplasmic vesicles, lysosomes, and cell membrane. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally N-glycosylated, ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Myeloproliferative disorder chronic with eosinophilia. This protein may also be known as IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, and CD140B.
The detection range for different Platelet Derived Growth Factor Receptor Beta ELISA kits can vary, with some assays measuring target concentrations as low as 24.69 pg/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.