The following Cleavage And Polyadenylation Specific Factor 1 ELISA kits are useful research tools for the measurement of cleavage and polyadenylation specific factor 1 in biological samples. In humans this protein is encoded by the CPSF1 gene. This protein is a known component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. The canonical protein structure is reported to have an amino acid length of 1443 residues, a mass of 160.9 kDa, and is a member of the CPSF1 protein family. Its subcellular location is known to be in the nucleus. In addition, it is found to be widely expressed, with high expression in the retina. The gene encoding this protein has been associated with the disease, Myopia. This protein may also be known as HSU37012, MYP27, P/cl.18, cleavage and polyadenylation specificity factor subunit 1, and CPSF160.
The detection range for different Cleavage And Polyadenylation Specific Factor 1 ELISA kits can vary, with some assays measuring target concentrations as low as 10 ng/L and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.