The following Suppressor of Cytokine Signaling 1 ELISA kits are useful research tools for the measurement of suppressor of cytokine signaling 1 in biological samples. In humans this protein is encoded by the SOCS1 gene. This protein is known to be an important negative regulator of type I and type II interferon (IFN) signaling, as well as that of other cytokines, including IL2, IL4, IL6 and leukemia inhibitory factor (LIF). The canonical protein structure is reported to have an amino acid length of 211 residues, a mass of 23.6 kDa, and is a member of the SOCS1 protein family. Its subcellular location is known to be in the nucleus and cytoplasmic vesicles. In addition, it is reported to be expressed in all tissues with high expression in spleen, small intestine and peripheral blood leukocytes. The gene encoding this protein has been associated with the disease, Autoinflammatory syndrome. This protein may also be known as CIS1, CISH1, JAB, SSI-1, SSI1, TIP-3, TIP3, and AISIMD.
There are Suppressor of Cytokine Signaling 1 ELISA kits that can detect a target at concentrations as low as 62.5 pg/mL and as high as 30 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.