The following phosphomevalonate kinase ELISA kits are useful research tools for the measurement of phosphomevalonate kinase in biological samples. In humans this protein is encoded by the PMVK gene. This protein is known to catalyze the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites. The canonical protein structure is reported to have an amino acid sequence of 192 residues and a mass of 22 kDa. Its subcellular location is known to be in the cytoplasm. The gene encoding this protein has been associated with the disease, Porokeratosis. This protein may also be known as PMK, PMKA, PMKASE, POROK1, testis tissue sperm-binding protein Li 95mP, and HUMPMKI.
There are phosphomevalonate kinase ELISA kits that can detect a target at concentrations as low as 0.313 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.