HR ELISA kits are immunoassay tools for the measurement of the protein HR lysine demethylase and nuclear receptor corepressor, which is encoded by the HR gene in humans. Functionally, this protein is reported to be a histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. The canonical protein structure is reported to have an amino acid sequence of 1189 residues and a mass of 127.5 kDa. It is known to be localized in the nucleus. As many as 2 protein isoforms have been reported. The HR gene has been associated with the disease, Alopecia universalis congenita. Other alias names for this target include [histone H3]-dimethyl-L-lysine(9) demethylase hairless, hair growth associated, hairless homolog, protein hairless, and lysine-specific demethylase hairless.
The detection range for different HR ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.