APEX2 ELISA kits are immunoassay tools for the measurement of the protein apurinic/apyrimidinic endodeoxyribonuclease 2, which is encoded by the APEX2 gene in humans. Functionally, this protein is known to function as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. The canonical protein structure is reported to have an amino acid length of 518 residues, a mass of 57.4 kDa, and is a member of the DNA repair enzymes AP/ExoA protein family. It is known to be localized in the nucleus, mitochondria, and cytoplasm and is reported to be highly expressed in the brain and kidney. Other alias names for this target include APEXL2, XTH2, ZGRF2, DNA-(apurinic or apyrimidinic site) endonuclease 2, AP endonuclease 2, and APE2.
There are APEX2 ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.