SAG ELISA kits are immunoassay tools for the measurement of the protein S-antigen visual arrestin, which is encoded by the SAG gene in humans. Functionally, this protein is known to bind to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (By similarity). The canonical protein structure is reported to have an amino acid length of 405 residues, a mass of 45.1 kDa, and is a member of the Arrestin protein family. It is known to be localized in the cell projections and membrane and is notably expressed in retina, in the proximal portion of the outer segment of rod photoreceptor cells. The SAG gene has been associated with the disease, Night blindness. Other alias names for this target include RP96, S-arrestin, 48 kDa protein, S-antigen; retina and pineal gland (arrestin), arrestin 1, and RP47.
The detection range for different SAG ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 25 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.