KYAT1 ELISA kits are immunoassay tools for the measurement of the protein kynurenine aminotransferase 1, which is encoded by the KYAT1 gene in humans. Functionally, this protein is known to catalyze the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. The canonical protein structure is reported to have an amino acid length of 422 residues, a mass of 47.9 kDa, and is a member of the Class-I pyridoxal-phosphate-dependent aminotransferase protein family. It is known to be localized in the cytoplasm. As many as 3 protein isoforms have been reported. Other alias names for this target include GTK, KATI, kynurenine--oxoglutarate transaminase 1, beta-lysase, kidney, and CCBL1.
The detection range for different KYAT1 ELISA kits can vary, with some assays measuring target concentrations as low as 78.1 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.