The following Cbl proto-oncogene ELISA kits are useful research tools for the measurement of Cbl proto-oncogene in biological samples. In humans this protein is encoded by the CBL gene. This protein is a reported adaptor protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. The canonical protein structure is reported to have an amino acid sequence of 906 residues and a mass of 99.6 kDa. Its subcellular location is known to be in the cell membrane, golgi, and cytoplasm. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia. This protein may also be known as CBL2, FRA11B, NSLL, RNF55, E3 ubiquitin-protein ligase CBL, and C-CBL.
Some Cbl proto-oncogene ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.