12-HETE ELISA kits are assays designed to detect 12-hydroxyeicosatetraenoic acid (12-HETE), a product of arachidonic acid metabolism. 12-HETE is involved in localized paracrine and endocrine signaling, changing cells around them in response to disturbances. Receptors such as the G protein-coupled receptor GPR31 show high affinity towards this compound. 12-HETE has been associated with inflammatory diseases, diabetes, cancer, and tumor metastasis. Visit the supplier page for more information about detection target, range, and reactivity.