LRRC8A ELISA kits are immunoassay tools for the measurement of the protein leucine rich repeat containing 8 VRAC subunit A, which is encoded by the LRRC8A gene in humans. Functionally, this protein is an important component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The canonical protein structure is reported to have an amino acid length of 810 residues, a mass of 94.2 kDa, and is a member of the LRRC8 protein family. It is known to be localized in the lysosomes and cell membrane and is reported to be expressed in the brain, kidney, ovary, lung, liver, heart, and fetal brain and liver. The protein has been noted to be post-translationally N-glycosylated. The LRRC8A gene has been associated with the disease, Agammaglobulinemia. Other alias names for this target include leucine rich repeat containing 8 family member A, leucine-rich repeat-containing protein 8A, swelling protein 1, and volume-regulated anion channel subunit LRRC8A.
There are LRRC8A ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.