Retinoic Acid ELISA kits are assays designed to measure levels of the metabolite retinoic acid in biological samples, such as plasma, serum, culture extracts, and cell lysates. Retinoic acid (RA), a metabolite of vitamin A1, plays a crucial role in growth and development. It binds the retinoic acid receptor (RAR), which is bound to DNA as a heterodimer with the retinoid X receptor (RXR) in regions called retinoic acid response elements (RAREs). This binding influences the conformation of RAR, modulating the transcriptional activity of nearby genes. Retinoic acid is involved in the induction of neural differentiation, motor neuron axon outgrowth and neural patterning during development. Click on the ELISA products below and visit the supplier for more information, including assay sensitivity and target specificity.
1 Human Metabolome Database (HMDB) v5.0