CRB1 ELISA kits are immunoassay tools for the measurement of the protein crumbs cell polarity complex component 1, which is encoded by the CRB1 gene in humans. Functionally, this protein is reported to play a role in in photoreceptor morphogenesis in the retina (By similarity). The canonical protein structure is reported to have an amino acid length of 1406 residues, a mass of 154.2 kDa, and is a member of the Crumbs protein family. It is known to be localized in the cell membrane and is secreted. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The CRB1 gene has been associated with the disease, Retinitis pigmentosa. Other alias names for this target include CRB1-B, CRB1-C, LCA8, RP12, protein crumbs homolog 1, and CRB1-A.
The detection range for different CRB1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.