MITF ELISA kits are immunoassay tools for the measurement of the protein melanocyte inducing transcription factor, which is encoded by the MITF gene in humans. Functionally, this protein is reported to be a transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. The canonical protein structure is reported to have an amino acid length of 526 residues, a mass of 58.8 kDa, and is a member of the MiT/TFE protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be expressed in melanocytes. As many as 12 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The MITF gene has been associated with the disease, Waardenburg syndrome. Other alias names for this target include COMMAD, MI, MITF-A, WS2, WS2A, bHLHe32, microphthalmia-associated transcription factor, and CMM8.
The detection range for different MITF ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.