The following gasdermin E ELISA kits are useful research tools for the measurement of gasdermin E in biological samples. In humans this protein is encoded by the GSDME gene. This protein has been described to function in TNF-mediated cellular signaling pathways and viral immune response. The canonical protein structure is reported to have an amino acid length of 496 residues, a mass of 54.6 kDa, and is a member of the Gasdermin protein family. Its subcellular location is known to be in the cell membrane and cytoplasm. In addition, it is notably expressed in cochlea. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally cleaved. The gene encoding this protein has been associated with the disease, Deafness. This protein may also be known as ICERE-1, DFNA5, deafness associated tumor suppressor, inversely correlated with estrogen receptor expression 1, non-syndromic hearing impairment protein 5, and DFNA5.
The detection range for different gasdermin E ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.