PABPN1 ELISA kits are immunoassay tools for the measurement of the protein poly(A) binding protein nuclear 1, which is encoded by the PABPN1 gene in humans. Functionally, this protein is reported to be involved in 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (By similarity). The canonical protein structure is reported to have an amino acid sequence of 306 residues and a mass of 32.7 kDa. It is known to be localized in the nucleus and cytoplasm and is ubiquitously expressed across many tissue types. As many as 3 protein isoforms have been reported. The PABPN1 gene has been associated with the disease, Oculopharyngeal muscular dystrophy. Other alias names for this target include PAB2, PABII, PABP-2, PABP2, polyadenylate-binding protein 2, and OPMD.
Some PABPN1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.