The following extra spindle pole bodies like 1, separase ELISA kits are useful research tools for the measurement of extra spindle pole bodies like 1, separase in biological samples. In humans this protein is encoded by the ESPL1 gene. This protein is reported to be a caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. The canonical protein structure is reported to have an amino acid sequence of 2120 residues and a mass of 233.2 kDa. Its subcellular location is known to be in the nucleus and cytoplasm. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally cleaved and phosphorylated. This protein may also be known as SEPA, separin, caspase-like protein ESPL1, extra spindle pole bodies 1, separase, extra spindle pole bodies homolog 1, and ESP1.
The detection range for different extra spindle pole bodies like 1, separase ELISA kits can vary, with some assays measuring target concentrations as low as 0.312 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.