PRF1 ELISA kits are immunoassay tools for the measurement of the protein perforin 1, which is encoded by the PRF1 gene in humans. Functionally, this protein is reported to be a pore-forming protein that plays a key role in granzyme-mediated programmed cell death, and in defense against virus-infected or neoplastic cells. The canonical protein structure is reported to have an amino acid length of 555 residues, a mass of 61.4 kDa, and is a member of the Complement C6/C7/C8/C9 protein family. It is known to be localized in the cell membrane and is secreted. The protein has been noted to be post-translationally N-glycosylated. The PRF1 gene has been associated with the disease, Hemophagocytic lymphohistiocytosis. Other alias names for this target include P1, PFP, cytolysin, lymphocyte pore-forming protein, perforin 1 (pore forming protein), and HPLH2.
Some PRF1 ELISA kits can detect targets at levels as low as 7.8 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.