The following Eukaryotic Translation Initiation Factor 4E ELISA kits are useful research tools for the measurement of eukaryotic translation initiation factor 4E in biological samples. In humans this protein is encoded by the EIF4E gene. This protein is known to recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. The canonical protein structure is reported to have an amino acid length of 217 residues, a mass of 25.1 kDa, and is a member of the Eukaryotic initiation factor 4E protein family. Its subcellular location is known to be in the nucleus and cytoplasm. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. The gene encoding this protein has been associated with the disease, Autism. This protein may also be known as CBP, EIF4EL1, EIF4F, eIF-4F 25 kDa subunit, and AUTS19.
The detection range for different Eukaryotic Translation Initiation Factor 4E ELISA kits can vary, with some assays measuring target concentrations as low as 7 ng/L and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.