The following Hepatocyte Nuclear Factor 4 alpha ELISA kits are useful research tools for the measurement of hepatocyte nuclear factor 4 alpha in biological samples. In humans this protein is encoded by the HNF4A gene. This protein is a reported transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes. The canonical protein structure is reported to have an amino acid length of 474 residues, a mass of 52.8 kDa, and is a member of the Nuclear hormone receptor protein family. Its subcellular location is known to be in the nucleus. As many as 7 protein isoforms have been reported. In certain instances, it is also post-translationally acetylated and phosphorylated. The gene encoding this protein has been associated with the disease, Maturity-onset diabetes of the young. This protein may also be known as HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, and FRTS4.
There are Hepatocyte Nuclear Factor 4 alpha ELISA kits that can detect a target at concentrations as low as 31 pg/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.