The following inosine triphosphatase ELISA kits are useful research tools for the measurement of inosine triphosphatase in biological samples. In humans this protein is encoded by the ITPA gene. This protein is a reported pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The canonical protein structure is reported to have an amino acid length of 194 residues, a mass of 21.4 kDa, and is a member of the HAM1 NTPase protein family. Its subcellular location is known to be in the cytoplasm. In addition, it is ubiquitously expressed across many tissue types. As many as 3 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Inosine triphosphate pyrophosphohydrolase deficiency. This protein may also be known as DEE35, HLC14-06-P, ITPase, My049, NTPase, dJ794I6.3, inosine triphosphate pyrophosphatase, and C20orf37.
Some inosine triphosphatase ELISA kits can detect targets at levels as low as 0.1 ng/mL and as high as 50 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.