COL4A1 ELISA kits are immunoassay tools for the measurement of the protein collagen type IV alpha 1 chain, which is encoded by the COL4A1 gene in humans. Functionally, this protein is known to be involved in brain development and epithelial cell differentiation. The canonical protein structure is reported to have an amino acid length of 1669 residues, a mass of 160.6 kDa, and is a member of the Type IV collagen protein family. It is known to be localized in the extracellular matrix and is secreted and is reported to be highly expressed in placenta. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally O-glycosylated and cleaved. The COL4A1 gene has been associated with the disease, Hereditary angiopathy with nephropathy aneurysms and muscle cramps. Other alias names for this target include BSVD1, COL4A1s, PADMAL, RATOR, collagen alpha-1(IV) chain, COL4A1 NC1 domain, arresten, and BSVD.
The detection range for different COL4A1 ELISA kits can vary, with some assays measuring target concentrations as low as 23.4 pg/mL and as high as 1000 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.