PDK3 ELISA kits are immunoassay tools for the measurement of the protein pyruvate dehydrogenase kinase 3, which is encoded by the PDK3 gene in humans. Functionally, this protein is reported to inhibit pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. The canonical protein structure is reported to have an amino acid length of 406 residues, a mass of 46.9 kDa, and is a member of the PDK/BCKDK protein kinase protein family. It is known to be localized in the mitochondria and is found to be expressed in heart, skeletal muscle, spinal cord, as well as fetal and adult brain. As many as 2 protein isoforms have been reported. The PDK3 gene has been associated with the disease, Charcot-Marie-Tooth disease. Other alias names for this target include GS1-358P8.4, pyruvate dehydrogenase kinase, isozyme 3, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, pyruvate dehydrogenase kinase, isoenzyme 3, and CMTX6.
There are PDK3 ELISA kits that can detect a target at concentrations as low as 31.2 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.