RSPO3 ELISA kits are immunoassay tools for the measurement of the protein R-spondin 3, which is encoded by the RSPO3 gene in humans. Functionally, this protein is reported to be an activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. The canonical protein structure is reported to have an amino acid length of 272 residues, a mass of 30.9 kDa, and is a member of the R-spondin protein family. It is known to be secreted and is ubiquitously expressed across many tissue types. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. Other alias names for this target include protein with TSP type-1 repeat, roof plate-specific spondin-3, thrombospondin type-1 domain-containing protein 2, thrombospondin, type I, domain containing 2, and R-spondin 3 homolog.
The detection range for different RSPO3 ELISA kits can vary, with some assays measuring target concentrations as low as 2 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.