The following Argininosuccinate Lyase ELISA kits are useful research tools for the measurement of argininosuccinate lyase in biological samples. In humans this protein is encoded by the ASL gene. This protein is known to catalyze the reversible cleavage of L-argininosuccinate to fumarate and L-arginine, an intermediate step reaction in the urea cycle mostly providing for hepatic nitrogen detoxification into excretable urea as well as de novo L-arginine synthesis in nonhepatic tissues. The canonical protein structure is reported to have an amino acid length of 464 residues, a mass of 51.7 kDa, and is a member of the Lyase 1 protein family. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally acetylated. The gene encoding this protein has been associated with the disease, Argininosuccinic aciduria. This protein may also be known as argininosuccinase, arginosuccinase, and ASAL.
There are argininosuccinate lyase ELISA kits that can detect a target at concentrations as low as 0.078 ng/mL and as high as 90 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.