The following ATM serine/threonine kinase ELISA kits are useful research tools for the measurement of ATM serine/threonine kinase in biological samples. In humans this protein is encoded by the ATM gene. This protein is a serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. The canonical protein structure is reported to have an amino acid length of 3056 residues, a mass of 350.7 kDa, and is a member of the PI3/PI4-kinase protein family. Its subcellular location is known to be in the nucleus, cytoplasmic vesicles, and cytoplasm. In certain instances, it is also post-translationally acetylated and phosphorylated. The gene encoding this protein has been associated with the disease, Ataxia telangiectasia. This protein may also be known as ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1, and AT1.
Some ATM serine/threonine kinase ELISA kits can detect targets at levels as low as 15.6 pg/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.