The following ATR serine/threonine kinase ELISA kits are useful research tools for the measurement of ATR serine/threonine kinase in biological samples. In humans this protein is encoded by the ATR gene. This protein is a serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. The canonical protein structure is reported to have an amino acid length of 2644 residues, a mass of 301.4 kDa, and is a member of the PI3/PI4-kinase protein family. Its subcellular location is known to be in the nucleus. In addition, it is found to be widely expressed, with highest expression in testis. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. The gene encoding this protein has been associated with the disease, Seckel syndrome. This protein may also be known as FRP1, MEC1, SCKL, SCKL1, serine/threonine-protein kinase ATR, and FCTCS.
The detection range for different ATR serine/threonine kinase ELISA kits can vary, with some assays measuring target concentrations as low as 0.625 ng/mL and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.