The following MALT1 paracaspase ELISA kits are useful research tools for the measurement of MALT1 paracaspase in biological samples. In humans this protein is encoded by the MALT1 gene. This protein is a reported protease that enhances BCL10-induced activation: acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. The canonical protein structure is reported to have an amino acid length of 824 residues, a mass of 92.3 kDa, and is a member of the Peptidase C14B protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be highly expressed in peripheral blood mononuclear cells. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Immunodeficiency. This protein may also be known as MLT, MLT1, PCASP1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, MALT1 protease, and IMD12.
There are MALT1 paracaspase ELISA kits that can detect a target at concentrations as low as 1.56 ng/mL and as high as 100 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.