LBR ELISA kits are immunoassay tools for the measurement of the protein lamin B receptor, which is encoded by the LBR gene in humans. Functionally, this protein is known to catalyze the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. The canonical protein structure is reported to have an amino acid length of 615 residues, a mass of 70.7 kDa, and is a member of the ERG4/ERG24 protein family. It is known to be localized in the nucleus, ER, and cytoplasm and is reported to be expressed in the bone marrow, liver, heart, adrenal gland, lung, placenta and uterus. The protein has been noted to be post-translationally phosphorylated. The LBR gene has been associated with the disease, Pelger-Huet anomaly. Other alias names for this target include DHCR14B, LMN2R, PHA, PHASK, TDRD18, and C14SR.
There are LBR ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.