5-hydroxyindoleacetic acid ELISA kits are designed for the specific detection of 5-hydroxyindoleacetic acid in biological samples. 5-Hydroxyindoleacetic acid is a compound that is metabolized in humans and can be detected in CSF, urine, fecal, and serum samples. It has the chemical formula C10H9NO3 and belongs to the indole-3-acetic acid derivatives class of molecules. 5-Hydroxyindoleacetic acid (5-HIAA), an indole-3-acetic acid derivative, is a breakdown product of serotonin in humans and is excreted in urine. It is involved in enzymatic reactions, including biosynthesis from 5-hydroxyindoleacetaldehyde, conversion to 5-methoxyindoleacetate, and participation in tryptophan metabolism. Elevated urinary levels are associated with diseases like appendicitis and gastroenteritis, and it serves as a diagnostic marker for carcinoid tumors.
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1 Human Metabolome Database (HMDB) v5.0