YAP1 ELISA kits are immunoassay tools for the measurement of the protein Yes1 associated transcriptional regulator, which is encoded by the YAP1 gene in humans. Functionally, this protein is a reported transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The canonical protein structure is reported to have an amino acid length of 504 residues, a mass of 54.5 kDa, and is a member of the YAP1 protein family. It is known to be localized in the nucleus and cytoplasm. As many as 9 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The YAP1 gene has been associated with the disease, Coloboma. Other alias names for this target include YAP, YAP2, YAP65, YKI, transcriptional coactivator YAP1, and COB1.
Some YAP1 ELISA kits can detect targets at levels as low as 15.625 pg/mL and as high as 60 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.