APH1A ELISA kits are immunoassay tools for the measurement of the protein aph-1 homolog A, gamma-secretase subunit, which is encoded by the APH1A gene in humans. Functionally, this protein is reported to be a non-catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The canonical protein structure is reported to have an amino acid length of 265 residues, a mass of 29 kDa, and is a member of the APH-1 protein family. It is known to be localized in the ER and golgi and is widely expressed across many tissue types. As many as 3 protein isoforms have been reported. Other alias names for this target include APH-1, CGI-78, gamma-secretase subunit APH-1A, APH1A gamma secretase subunit, anterior pharynx defective 1 homolog A, and 6530402N02Rik.
Some APH1A ELISA kits can detect targets at levels as low as 20 ng/L and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.