The following Senataxin ELISA kits are useful research tools for the measurement of senataxin in biological samples. In humans this protein is encoded by the SETX gene. This protein is a suspected RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. The canonical protein structure is reported to have an amino acid length of 2677 residues, a mass of 302.9 kDa, and is a member of the DNA2/NAM7 helicase protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be highly expressed in skeletal muscle. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and sumoylated. The gene encoding this protein has been associated with the disease, Spinocerebellar ataxia. This protein may also be known as AOA2, SCAN2, SCAR1, STEX, Sen1, bA479K20.2, probable helicase senataxin, and ALS4.
Some Senataxin ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.