ADAMTS18 ELISA kits are immunoassay tools for the measurement of the protein ADAM metallopeptidase with thrombospondin type 1 motif 18, which is encoded by the ADAMTS18 gene in humans. Functionally, this protein is known to be involved in extracellular matrix organization and eye development. The canonical protein structure is reported to have an amino acid sequence of 1221 residues and a mass of 135.2 kDa. It is known to be localized in the extracellular matrix and is secreted and is reported to be expressed in fetal lung, liver, and kidney and in adult brain, prostate, submaxillary gland, and endothelium. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated and cleaved. The ADAMTS18 gene has been associated with the disease, Microcornea, myopic chorioretinal atrophy, and telecanthus. Other alias names for this target include disintegrin and metalloprotease-like protein, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 21, and A disintegrin and metalloproteinase with thrombospondin motifs 18.
There are ADAMTS18 ELISA kits that can detect a target at concentrations as low as 78 pg/mL and as high as 10 µg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.